Neat Image

[berrywise]

I actually prefer Noise Ninja over Neat Image, on my images it left more of the fine detail intact.

Same here. I find Neat Image to almost be like an air brushing tool in the way that it works. I find I've gotten better resuls with Noise Ninja.

[plugsnpixels]

I recently ran the main noise-reduction contenders on a blow-up of a grainy film scan and got these results. IMO, Noiseware and NoiseNinja did the best job.