Re: Question, please help
The Xsi also has more auto-focus points than the XS and a better burst capacity in jpg and raw formats. That second part means it can take more pictures in a quick burst than the XS. If you don't plan on doing anything with it where you will need to take a bunch of shots really close together then it's probably not an issue. Oh, I think the Xsi also had one more light metering type.
I was looking at both the XS and Xsi last summer and I did decide for me the extra was worth it and ended up with the Xsi. Yes your 75-300 should fit on either camera. I have a 35-80mm kit lens that came with an old Canon Rebel film SLR from mid-90's and it works on my Xsi.